ImmuneSigR - Immune Cell Signature Retrieval and Single-Cell Scoring
Provides a literature-derived database of immune cell
markers formatted as Gene Matrix Transposed (GMT) files. Users
can search immune cell signatures, retrieve marker lists,
export GMT files, create custom marker sets, and score
gene-by-cell expression matrices with dependency-free
rank-based or mean-expression methods. Cell subpopulations are
distinguished by their source PMIDs. For the core curation of
the lung cell atlas, see Travaglini et al. (2020)
<doi:10.1038/s41586-020-2922-4>. For the pan-cancer B cell
signatures, see Fitzsimons et al. (2024)
<doi:10.1016/j.ccell.2024.09.011>.
